For many of us, the day does not start until we made our first cup of coffee. It is a relaxing, energetic and one of the most consumed drinks in the world. But while your morning production may be harmless, it can increase the risk of side effects by specific medications in ways that reduce their effectiveness – or increase the risk of side effects.
From cold pills to antidepressants, the effect of caffeine on the body goes beyond rapid energy increase. Tea also contains caffeine but not at the same concentrations of coffee and does not appear to affect people in the same way.
Here’s what you need to know how coffee can interfere with your medications – and how you can be safe.
1 Cold and Influenza drugs
Caffeine is a stimulus, meaning it speeds up the central nervous system. Pseudoephedrine, a disinfectant in colds and flu such as SUDAFED, is also a stimulant. When gathering together, the effects can be strengthened – potentially leading to stains or restlessness, headaches, rapid heart rate and insomnia.
Many cold drugs currently contain added caffeine and increase these risks. Some studies also show that the composition of caffeine with quasi -feedin can increase blood sugar and body temperature, especially for people with diabetes.
The stimulant effects are also worrying about caffeine composition with ADHD drugs such as amphetamines or asthma drugs such as theophylline, which have a similar chemical structure to caffeine. Using them together may increase the risk of side effects such as rapid heart rate and sleep disorders.
2. Thyroid drug
Luothyroxine, standard treatment for low -motivated thyroid, is very sensitive to timing – and your morning coffee can be on the way. Studies show that drinking coffee soon after taking luteroxine can reduce it up to 50 %.
Caffeine enhances intestinal mobility (moving food and waste through the digestive tract) and gives the drug that provides less time to absorb it – and may also attach it to the stomach and make the body harder for the body. These effects reduce the bioavailability of the drug, which means that it is less likely to reach your blood where it is needed. This interaction with levothyroxine tablets is less likely to formulate.
In case of absorption, symptoms of hypothyroidism – including fatigue, weight gain and constipation – can be returned, even if you take your medication properly.
The same timing law applies to the osteoporosis class called base phosphonate, including alndronate and poured, which requires an empty stomach and about 30-60 minutes before eating or drink.
3. Antidepressant and anti -psychiatric drugs
The interaction between caffeine and mental health drugs can be more complex.
Selected inhibitors to restore serotonin (SSRIs), such as sertraline and cytalopram, are a type of antidepressant drugs that are widely used to treat depression, anxiety, and other psychiatric conditions. Laboratory studies show that caffeine can attach to these drugs in the stomach, reduce absorption and potentially affect them.
Triple -rings antidepressants (TCAs), such as amitriptyline and immapramine, are a floor of old antidepressants that work by affecting the level of neurotransmitters in the brain. They were one of the first developed antidepressants and are less commonly used today, compared to newer antidepressants such as SSRI, because of their potential for more side effects and more risk of taking overdose.
The TCAs are broken by the CYP1A2 liver enzyme, which also makes caffeine metabolis. Competition between the two can slow down drugs, increase side effects, or delay caffeine customs clearance, making you feel surprising or wire than usual.
Clazapine, anti -psychiatric, is also processed by CYP1A2. One study found that drinking two to three cups of coffee can increase blood levels by up to 97 %, potentially risks such as drowsiness, confusion or more serious complications.
4. Housing
Some prescription painkillers, such as those containing aspirin or paracetamol, include added caffeine. Coffee can quickly absorb these drugs by accelerating the speed of gastric and acidic emptying, which increases the absorption of some drugs such as aspirin.
While this may work faster to painkillers, it can also increase the risk of side effects such as stomach stimulation or bleeding, especially when combined with other caffeine sources. Although no serious cases have been reported, caution is still recommended.
5 heart medications
Caffeine can temporarily increase blood pressure and heart rate, typically three to four hours after taking.
For people who control hypertension or drugs that control irregular heart rhythms (arrhythmia), this may counteract the effects of the drug.
This does not mean that people with heart conditions should prevent coffee as a whole – but they must monitor how they affect their symptoms and consider the amount or displacement of Decaf if necessary.
What can you do?
Coffee may be part of your daily routine, but it is also a powerful chemical compound that can affect the process of processing the drug. Here is how to ensure its interference.
Take luteroxine or base phosphonates on an empty stomach with water and wait 30-60 minutes before drinking coffee or eating breakfast.
Be cautious with cold and flu medications, asthma treatments and ADHD medications, as caffeine can enhance the side effects.
If you are in antidepressant, anti -psychiatric or hypertensive drugs, discuss your caffeine habit with your doctor.
If you experience side effects such as restlessness, insomnia or heartbeat, consider reducing or choosing a caffeine -free option.
Everyone makes caffeine different – some people feel good after three cups, while others have only one side effects. Notice how your body responds and talks to your pharmacist or general practitioner if you feel tired.
If you are not sure that your medicine and coffee match well, ask your pharmacist or doctor. A short conversation may save your week of side effects or reduce your therapeutic effectiveness – and will help you enjoy it with peace.
Dipa Kamdar is a senior lecturer in pharmacy at the University of Kingston.
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